Affiliation:
1. C. H. Boehringer Sohn, Ingelheim, Abteilung Pharmacie
Abstract
Synthesis and several reactions of the N-aryl-1,4-benzodiazepine-mono-ones (8) are described. With the Sandmeyer-reaction of 3f, a substitution of the p-position of the N-phenyl ring may occur. The compounds exhibit only a slight action upon the central nervous system (CNS).
Cited by
9 articles.
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1. Tetrahydro- and Polyhydro-1,4-Benzodiazepines;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02
2. Dihydro-1,4-Benzodiazepines;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02
3. The synthesis of bicyclic 1,2,3,4-tetrahydro-1,4-benzodiazepin-5-ones from 2-(o-nitrobenzoyl)-1,2-thiazine-1-oxide precursors;Tetrahedron;2004-04
4. Versatile synthesis of chiral 2-substituted-5-oxo-1,2,3,4-tetrahydro-5H-1,4-benzodiazepines as novel scaffolds for peptidomimetic building;Tetrahedron;2003-06
5. Expedient One-Pot Synthesis of Novel Chiral 2-Substituted 5-Phenyl-1,4-benzodiazepine Scaffolds from Amino Acid-Derived Amino Nitriles;The Journal of Organic Chemistry;2003-05-01