Mixed-ligand complexes of copper(II) ions with L-glutamic acid in the systems with triamines and non-covalent interaction between bioligands in aqueous solution

Abstract

AbstractThe interactions between L-glutamic acid (Glu) and 1,7-diamino-4-azaheptan (3,3-tri) and 1,8-diamino-4-azaoktan (Spd) in metal-free systems and in the appropriate Cu(II) ions complexes were studied by potentiometric and spectral methods. The composition and overall stability constants of complexes forming in the systems studied were determined and the reactions centres were identified. In the complex formation conditions, the ligands have positive and negative reaction centres, which are also the potential sites of metal coordination. Below pH 7 in metal-free systems, the terminal amine groups from both triamines and the oxygen atoms from –C