Hyponatremia, bone mineral density and falls in the elderly; Results from AHAP study

Author:

Hosseini Seyed Reza1,Baghitabar Naghi2,Mirzapour Ali2,Oliaei Farshid3,Nooreddini Hajighorban2,Bijani Ali1,Mouodi Simin1

Affiliation:

1. Social Determinants of Health Research Center, Health Research Institute , Babol University of Medical Sciences , Babol , Iran

2. Faculty of Medicine , Babol University of Medical Sciences , Babol , Iran

3. Department of Internal Medicine , Babol University of Medical Sciences , Babol , Iran

Abstract

Abstract Background. Hyponatremia (HN) can be associated with osteoporosis, falls and bone fractures in the elderly. Recent researches demonstrated different results about the correlation of HN with bone mineral density and bone fractures. Methods. This analytic research came from the AHAP project in northern IRAN. All people aged 60 years and over were included in the study. Individuals with severe comorbidities and then who had concurrent conditions which could have impact on bone mineral densities (BMD) such as long-term use of steroids, calcium and/or vitamin D supplements, bisphosphonates, calcitonin, thiazides and hormonal medications were excluded. Results. One thousand and one hundred and thirteen older persons entered in the study. More than 10 percent of the participants had HN (serum Na+ level ≤ 137mEq/L). No significant difference has been observed between hyponatremic and nonhyponatremic individuals about their balance abilities; bone mineral density; incidence of falls and/or bone fracture during the previous 6 months; dependency in activities of daily living; and osteoporosis. Conclusion. HN was not a prevalent problem in older adults who met the inclusion criteria of this research. No significant difference has been observed between HN and bone mineral density and falls in the elderly.

Publisher

Walter de Gruyter GmbH

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