Affiliation:
1. Canyon Crest Academy , San Diego, California, 92130
Abstract
Abstract
The venerable process of cellular respiration is essential for cells to produce energy from glucose molecules, in order to carry out cellular work. The process is responsible for producing molecules of ATP, a molecule which is thermodynamically coupled with other biochemical and biophysical processes in order to provide energy for such processes to occur. While the process of cellular respiration is essential to biology, one cycle of the process occurs only in a matter of milliseconds, and so, it would be impractical to measure the time it takes for the process to occur through conventional means. Therefore, using concepts from reaction rate theory, particularly Marcus Theory of electron transfer, Michaelis-Menten kinetics for enzymatic catalysis, and the hard-sphere model of collision theory, I formulate and propose a mathematical approximation for the amount of time it takes for cellular respiration to occur. Through this heuristic approach, quantitatively knowing the amount of time it takes for one cycle of cellular respiration to occur could potentially have future applications in biological research.
Subject
Applied Mathematics,Computational Mathematics,Mathematical Physics,Molecular Biology,Biophysics
Reference22 articles.
1. [1] Athel Cornish-Bowden. One hundred years of michaelis–menten kinetics. Perspectives in Science, 4:3–9, 2015.
2. [2] Rouslan G Efremov, Rozbeh Baradaran, and Leonid A Sazanov. The architecture of respiratory complex i. Nature, 465(7297):441–445, 2010.
3. [3] Gregory J. Gatto Jr. Lubert Stryer Jeremy M. Berg, John L. Tymoczko. Biochemistry 8th Edition. W.H Freeman and Company, 2015.
4. [4] Hans Adolf Krebs and William Arthur Johnson. The role of citric acid in intermediate metabolism in animal tissues. FEBS letters, 117(S1):K2–K10, 1980.
5. [5] Xue-bing Li, Jun-dong Gu, and Qing-hua Zhou. Review of aerobic glycolysis and its key enzymes–new targets for lung cancer therapy. Thoracic cancer, 6(1):17–24, 2015.