A standardised FACS assay based on native, receptor transfected cells for the clinical diagnosis and monitoring of β1-adrenergic receptor autoantibodies in human heart disease

Author:

Bornholz Beatrice,Benninghaus Thomas,Reinke Yvonne,Felix Stephan B.,Roggenbuck Dirk,Jahns-Boivin Valérie,Jahns Roland,Boege Fritz

Abstract

Abstract: Autoantibodies against βGood laboratory practice (GLP)-conform measurement of βSensitivity and specificity of the novel procedure for high βThe novel assay possibly provides a tool to determine true prevalence and clinical impact of β

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry (medical),Clinical Biochemistry,General Medicine

Reference60 articles.

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2. Anti beta adrenoceptor autoantibodies analyzed in spontaneously beating neonatal rat heart myocyte cultures comparison of methods;Wallukat;Dev Biol,2001

3. Impact of human autoantibodies on beta adrenergic receptor conformation activity internalization;Bornholz;Cardiovasc Res,2013

4. CM dysfunction autoimmunity;Hohensinner;aging Aging Dis,2011

5. novel fluorescence method for the rapid detection of functional beta - adrenergic receptor autoantibodies in heart failure;Nikolaev VO;J Am Coll Cardiol,2007

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