Head-to-head comparison of 10 natriuretic peptide assays

Author:

Collin-Chavagnac Delphine,Dehoux Monique,Schellenberg François,Cauliez Bruno,Maupas-Schwalm Françoise,Lefevre Guillaume,on behalf of the Société Française

Abstract

AbstractThe aim of the study was to compare NT-proBNP and BNP levels in fresh samples from heart failure (HF) patients measured using 10 immunoassays and to assess their agreement.NT-proBNP (CobasH232The Pearson correlation coefficient ranged between 0.929 (TriageThis study stresses the lack of transferability of the results obtained using different techniques to measure BNP and NT-proBNP levels in fresh samples. Individual reference ranges and HF diagnostic cut-offs should be assessed for each commercial NP immunoassay. We recommend to systematically monitoring HF patients using the same assay (BNP or NT-proBNP) over the time.

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry (medical),Clinical Biochemistry,General Medicine

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