Author:
Fedosov Sergey N.,Brito Alex,Miller Joshua W.,Green Ralph,Allen Lindsay H.
Abstract
AbstractA novel approach to determine vitamin BWe used a database with all four markers (n=5211) plus folate measurements (n=972). A biomarkerThe predictive functionsWe provide equations that combine two, three or four biomarkers into one diagnostic indicator, thereby rescaling unmatched data into the same coordinate system. Adjustment of this indicator is required if serum folate is <10 nmol/L and tHcy is measured. Revised cut-points and guidelines for using this approach are provided.
Subject
Biochemistry, medical,Clinical Biochemistry,General Medicine
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