Efficient reporting of the estimated glomerular filtration rate without height in pediatric patients with cancer

Abstract

Abstract:Background:The updated bedside Schwartz equation requires constant, serum creatinine concentration and height measurements to calculate the estimated glomerular filtration rate (eGFR) in pediatric patients. Unlike the serum creatinine levels, obtaining height information from the laboratory information system (LIS) is not always possible in a clinical laboratory. Recently, the height-independent eGFR equation, the full age spectrum (FAS) equation, has been introduced. We evaluated the performance of height-independent eGFR equation in Korean children with cancer.Methods:A total of 250 children who underwent chromium-51-ethylenediamine tetra acetic-acid (Results:The FAS equation showed significantly lower bias (mL/min/1.73 mConclusions:The height-independent eGFR-FAS equation was less biased and as accurate as the updated Schwartz equation in Korean children. The use of the height-independent eGFR equation will allow for efficient reporting of eGFR through the LIS in clinical laboratories.