Performance of point-of-care HbA1c test devices: implications for use in clinical practice – a systematic review and meta-analysis

Author:

Hirst Jennifer A.,McLellan Julie H.,Price Christopher P.,English Emma,Feakins Benjamin G.,Stevens Richard J.,Farmer Andrew J.

Abstract

AbstractBackground:Point-of-care (POC) devices could be used to measure hemoglobin AMethods:Medline, Embase and Web of Science databases were searched in June 2015 for published reports comparing POC HbAResults:Two researchers independently reviewed 1739 records for eligibility. Sixty-one studies were included in the meta-analysis of mean bias. Devices evaluated were A1cgear, A1cNow, Afinion, B-analyst, Clover, Cobas b101, DCA 2000/Vantage, HemoCue, Innovastar, Nycocard, Quo-Lab, Quo-Test and SDA1cCare. Nine devices had a negative mean bias which was significant for three devices. There was substantial variability in bias within devices. There was no difference in bias between clinical or laboratory operators in two devices.Conclusions:This is the first meta-analysis to directly compare performance of POC HbA

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry, medical,Clinical Biochemistry,General Medicine

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