Potential diagnostic biomarkers for schizophrenia

Author:

Yue Weihua1234ORCID,Huang Hailiang567,Duan Jubao89

Affiliation:

1. Institute of Mental Health, Peking University Sixth Hospital , Beijing , China

2. National Clinical Research Center for Mental Disorders & NHC Key Laboratory of Mental Health (Peking University) and Chinese Academy of Medical Sciences Research Unit , Beijing , China

3. PKU-IDG/McGovern Institute for Brain Research, Peking University , Beijing , China

4. Chinese Institute for Brain Research , Beijing , China

5. Analytic and Translational Genetics Unit, Massachusetts General Hospital , Boston , MA , USA

6. Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard , Cambridge , MA , USA

7. Department of Medicine , Harvard Medical School , Boston , MA , USA

8. Center for Psychiatric Genetics, NorthShore University Health System , Evanston , IL , USA

9. Department of Psychiatry and Behavioral Neurosciences , University of Chicago , Chicago , IL , USA

Abstract

Abstract Schizophrenia (SCH) is a complex and severe mental disorder with high prevalence, disability, mortality and carries a heavy disease burden, the lifetime prevalence of SCH is around 0.7%–1.0%, which has a profound impact on the individual and society. In the clinical practice of SCH, key problems such as subjective diagnosis, experiential treatment, and poor overall prognosis are still challenging. In recent years, some exciting discoveries have been made in the research on objective biomarkers of SCH, mainly focusing on genetic susceptibility genes, metabolic indicators, immune indices, brain imaging, electrophysiological characteristics. This review aims to summarize the biomarkers that may be used for the prediction and diagnosis of SCH.

Publisher

Walter de Gruyter GmbH

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3