Adiponectin: friend or foe in obesity and inflammation-Reference-Cited by-同舟云学术

Adiponectin: friend or foe in obesity and inflammation

Published:2022-07-01 Issue:4 Volume:2 Page:349-362
ISSN:2749-9642
Container-title:Medical Review
language:en
Short-container-title:

Author:

Luo Liping¹²^ORCID,Liu Meilian¹^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology , University of New Mexico Health Sciences Center , Albuquerque , NM , USA

2. Department of Endocrinology , Endocrinology Research Center, Xiangya Hospital, Central South University , Changsha , Hunan , China

Abstract

AbstractAdiponectin is an adipokine predominantly produced by fat cells, circulates and exerts insulin-sensitizing, cardioprotective and anti-inflammatory effects. Dysregulation of adiponectin and/or adiponectin signaling is implicated in a number of metabolic diseases such as obesity, insulin resistance, diabetes, and cardiovascular diseases. However, while the insulin-sensitizing and cardioprotective effects of adiponectin have been widely appreciated in the field, the obesogenic and anti-inflammatory effects of adiponectin are still of much debate. Understanding the physiological function of adiponectin is critical for adiponectin-based therapeutics for the treatment of metabolic diseases.

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/mr-2022-0002/pdf

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