A clean and simple method for deprotection of phosphines from borane complexes-Reference-Cited by-同舟云学术

A clean and simple method for deprotection of phosphines from borane complexes

Published:2017-06-22 Issue:1 Volume:90 Page:49-62
ISSN:1365-3075
Container-title:Pure and Applied Chemistry
language:en
Short-container-title:

Author:

Demchuk Oleg M.¹^ORCID,Jasinski Radomir²,Strzelecka Dorota¹,Dziuba Kamil¹,Kula Karolina²,Chrzanowski Jacek³,Krasowska Dorota³

Affiliation:

1. Department of Organic Chemistry , Maria Curie-Sklodowska University , 33 Gliniana St. , Lublin 20-614 , Poland

2. Institute of Organic Chemistry and Technology , Warszawska 24, Cracow University of Technology , Cracow 31-155 , Poland

3. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences , Sienkiewicza 112, 90-363 Lodz , Poland

Abstract

Abstract Simple, efficient, clean, and stereospecific protocols of protection of phosphorus atom with borane and deprotection from the borane complexes of the tertiary phosphines in mild conditions are reported. The proposed protection/deprotection reactions tolerate a range of functional groups and lead to pure products with excellent yield with no need for application of chromatographic or crystallisation purification procedures. For the first time mechanisms of the reactions of phosphine protection and deprotection have been studied based on experimental kinetic data as well as quantumchemical calculations, which allows designing reaction conditions suitable for a given substrate.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/pac-2017-0313/pdf

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