Noninvasive Assessment of Coronary Artery Disease: Fractional Flow Reserved Derived from Coronary Computed Tomography Angiography (FFRCT)-Reference-Cited by-同舟云学术

Noninvasive Assessment of Coronary Artery Disease: Fractional Flow Reserved Derived from Coronary Computed Tomography Angiography (FFRCT)

Published:2016-09-01 Issue:2 Volume:1 Page:137-141
ISSN:2501-8132
Container-title:Journal of Interdisciplinary Medicine
language:en
Short-container-title:

Author:

Rațiu Mihaela¹²,Rat Nora³,Condrea Sebastian¹,Stănescu Alexandra¹,Opincariu Diana¹,Mester András¹,Jani Laura¹,Benedek Imre³,Benedek Theodora³

Affiliation:

1. Center of Advanced Research in Multimodality Cardiac Imaging, Cardio Med Medical Center, Tîrgu Mureș, Romania

2. Clinic of Radiology, University of Medicine and Pharmacy, Tîrgu Mureș, Romania

3. Clinic of Cardiology, University of Medicine and Pharmacy, Tîrgu Mureș, Romania

Abstract

Abstract Invasive coronary angiography (ICA) completed by fractional flow reserve (FFR) assessment represents the main procedure that is performed in the decision process for coronary revascularization. Coronary Computed Tomography Angiography (CCTA) is an effective method used in the noninvasive anatomic assessment of coronary artery disease (CAD). However, CCTA tends to overestimate and does not offer hemodynamic data about the coronary lesions. Recent progresses made in the research involving computational fluid dynamics and image modeling permit the evaluation of FFRCT noninvasively, using data obtained in a standard CCTA. Studies have shown an improved precision and discrimination of FFRCT compared to CCTA for the diagnosis of significant coronary artery stenosis. In this review, we aimed to summarize the role of CCTA in CAD evaluation, the impact of FFRCT, the scientific basis of this novel method and its potential clinical applications.

Publisher

Walter de Gruyter GmbH

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