Author:
Zhou Yi,Wu Hong-Hui,Ping Yuan,Gao Jian-Qing
Abstract
Abstract
Functional biomaterials that are capable of effectively carrying therapeutic agents and specifically delivering therapeutics to pathological sites have been widely investigated over decades. Recently, cellular carriers and cell derivative-based bio-hybrid delivery systems have drawn extensive attention as a promising branch of therapeutic delivery systems, owing to their low immunogenicity and intriguing biomimetic capabilities. Various approaches for the fabrication of these biomimetic carriers have been developed, and some products have already been commercialized as well. In this review, we summarized various processing methods for engineering cell-derived biomimetic drug delivery systems, and discussed their future outlooks.
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference165 articles.
1. characterization of artificial nanoerythrosomes derived from erythrocyte ghost membranes;Deák;Surf
2. Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery;Song;Control Release,1997
3. enzyme and peptide delivery using erythrocytes as carriers;Millan;Drug Control Release,2004
4. Bringing next - generation therapeutics to the clinic through synthetic biology;Bugaj;Curr Opin Chem Biol,2012
5. Acid Mediated;Vasconcellos;Adhesion Biomacromolecules,2010
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