Oxidative Metabolism of the Trifluoromethoxy Moiety of OSI-930
Author:
Publisher
Walter de Gruyter GmbH
Subject
Pharmacology (medical)
Link
https://www.degruyter.com/document/doi/10.1515/DMDI.2009.24.2-4.95/pdf
Reference25 articles.
1. Kinetic isotope effects on cytochrome P-450-catalyzed oxidation reactions. The oxidative O-dealkylation of 7-ethoxycoumarin.
2. Effects of Fluorine Substitution on Drug Metabolism: Pharmacological and Toxicological Implications
3. Novel Metabolic Pathway of Arylethers by Cytochrome P450: Cleavage of the Oxygen-Aromatic Ring Bond Accompanying ipso-Substitution by the Oxygen-Atom of the Active Species in Cytochrome P450 Models and Cytochrome P450
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