BETAMETHASONE cream to treat diapers rash causing Cushing syndrome

Author:

Ali Tooba1ORCID,Habib Ashna1ORCID,Zohair Muhammad1,Aman Lubna2

Affiliation:

1. Dow University of Health Sciences , Karachi , Pakistan

2. Department of Pediatric Nephrology , National Institute of Child Health , Karachi , Sindh , Pakistan

Abstract

Abstract Objective Betamethasone causing iatrogenic Cushing’s syndrome (CS) in infants are rarely reported. Case Presentation ∗ In this case report, there were severe signs of CS, such as considerable weight acceleration and concurrent height deceleration, hirsutism and ecchymosis of the face, and buffalo pad, which are often found in adults. ∗ Clobetasol propionate, diflucortolone valerate, and dexamethasone nasal sprays were used in the majority of previously reported cases of corticosteroid abuse, whereas this is the first case of CS in an infant as a result of the use of betamethasone cream, also known as betnesol, which is frequently used by mothers in developing countries as a treatment for rashes. ∗ In this instance, a severe medication interaction caused by systemic betamethasone cream buildup led to the creation of CS. For the professionals, these patients are a challenge because of drug use without prescription. Conclusion Topical corticosteroid usage puts infants at risk for CS. Because of excessive betamethasone treatment in this child with diaper dermatitis, he acquired CS. It is said to draw attention to the risks of self-medication in developing nations.

Publisher

Walter de Gruyter GmbH

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Pediatrics, Perinatology and Child Health

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Betamethasone;Reactions Weekly;2023-06-10

2. Potential usefulness of assessing serum betamethasone levels during betamethasone therapy;Journal of Pediatric Endocrinology and Metabolism;2023-06-05

3. Side effects of agents that influence corticotrophins, corticosteroids, and prostaglandins;Side Effects of Drugs Annual;2023

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