Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1-Reference-Cited by-同舟云学术

Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1

Published:2022-11-24 Issue:0 Volume:0 Page:
ISSN:0334-018X
Container-title:Journal of Pediatric Endocrinology and Metabolism
language:en
Short-container-title:

Author:

Cui Joy¹,Halpin Kelsee²³^ORCID,Paprocki Emily²³

Affiliation:

1. Kansas City University College of Medicine , Kansas City , MO, USA

2. Division of Endocrinology , Children’s Mercy Kansas City , Kansas City , MO , USA

3. School of Medicine , University of Missouri-Kansas City , Kansas City , MO, USA

Abstract

Abstract Objectives Classic treatment for syndrome of inappropriate antidiuretic hormone (SIADH) is fluid restriction. However, this is not ideal for infants who need large fluid volumes to ensure adequate caloric intake for growth. The use of urea has not been thoroughly studied in children. Case presentation This infant had SIADH complicated by poor growth, solitary central incisor, and NF1. Following failed attempts to correct hyponatremia with fluid restriction and other therapeutics, urea normalized sodium levels and allowed liberalization of formula volumes, which resulted in improved weight gain. Conclusions Urea is a safe, cost-effective, long-term treatment for SIADH in infants who are unable to fluid restrict due to caloric goals.

Publisher

Walter de Gruyter GmbH

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Pediatrics, Perinatology and Child Health

Link

https://www.degruyter.com/document/doi/10.1515/jpem-2022-0294/pdf

Reference13 articles.

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