Evaluation of bladder dysfunction in children and adolescents with type 1 diabetes mellitus by uroflowmetry
Author:
Onder Camas Asan1ORCID, Özel Şeyhmus Kerem2, Kocabey Sütçü Zümrüt1ORCID, Hepokur Merve1, Emeksiz Hamdi Cihan1
Affiliation:
1. Pediatric Endocrinology Clinic , Medeniyet University Goztepe Prof. Dr. Suleyman Yalcin City Hospital , Istanbul , Turkey 2. Pediatric Surgery Clinic , Medeniyet University Goztepe Prof. Dr. Suleyman Yalcin City Hospital , Istanbul , Turkey
Abstract
Abstract
Objectives
Diabetic cystopathy is a condition characterized by decreased bladder sensitivity, increased bladder capacity, decreased bladder contractility and increased residual urine volume. It can also be considered as an early indicator of autonomic dysfunction. In this study, it was aimed to evaluate bladder functions by uroflowmetry in children and adolescents with the diagnosis of type 1 diabetes mellitus.
Methods
Type 1 diabetes mellitus children and adolescents were applied uroflowmetry and post-void residual urine volumes were evaluated. The physical examination findings of the patients and the laboratory data of diabetes control were obtained from the clinic files.
Results
A total of 51 cases aged 72–216 (155.6 ± 35.4) months were enrolled into the study. Diabetes age of the cases was 66.5 ± 46.2(13–180) months. The last one year average of HbA1c of the patients was found to be 9.7 ± 1.9%. A total of 9.8% had good, 39.2% moderate and 51% poor metabolic control, respectively. While urodynamic evaluation was normal in 36 (70.6%) of 51 participants, voiding dysfunction was found in 15. There was no statistically significant difference between groups with and without voiding dysfunction in terms of age, gender, duration of diabetes, metabolic control and HbA1c values.
Conclusions
It is very important to follow up patients with type 1 diabetes mellitus in terms of autonomic dysfunction. Diabetic bladder clinic, which can be observed independently of diabetes duration and metabolic control, is also included in this status. Urodynamic evaluation will be helpful both in demonstrating bladder dysfunction and in preventing possible complications.
Publisher
Walter de Gruyter GmbH
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Pediatrics, Perinatology and Child Health
Reference21 articles.
1. Davis, EM, Kahkoska, AR, Jefferies, C, Dabelea, D, Balde, N, Seth, A, et al.. Definition, epidemiology and clasification of diabetes in children and adolescents. ISPAD clinical practice consensus guidelines. Pediatr Diabetes 2018;19:7–19. https://doi.org/10.1111/pedi.12773. 2. Yesilkaya, E, Cinaz, P, Andıran, N, Bideci, A, Hatun, Ş, Sarı, E, et al.. First report on the nationwide incidence and prevalence of type 1 diabetes among children in Turkey. Diabet Med 2017;34:405–10. https://doi.org/10.1111/dme.13063. 3. Donaghue, CK, Marcovecchio, ML, Wadwa, RP, Chew, EY, Wong, TY, Calliari, LE, et al.. ISPAD clinical practice consensus guidelines 2018: microvascular and macrovascular complications in children and adolescents. Pediatr Diabetes 2018;19:262–74. https://doi.org/10.1111/pedi.12742. 4. Pop-Busui, R, Braffett, BH, Zinman, B, Martin, C, White, NH, Herman, WH, et al.. Cardiovascular autonomic neuropathy and cardiovascular outcomes in the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study. Diabetes Care 2017;40:94–100. https://doi.org/10.2337/dc16-1397. 5. Mmonu, NA, Pop-Busui, R, Wessells, H, Sarma, AV. Autonomic neuropathy and urologic complications in diabetes. Auton Neurosci 2020;229:102736. https://doi.org/10.1016/j.autneu.2020.102736.
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