Dimere Naphthochinone, 17. Synthesen von Stypandron und Dianellinon / Dimeric Naphthoquinones, 17. Synthesis of Stypandrone and Dianellinone

Abstract

The naphthoquinone stypandrone (2b) ist synthesized via the intermediates 5a, 6a and 6b. Selective monoalkylation of its hydroquinone yields the monoether 12b, which, on phenol oxida­tion and oxidative dealkylation, leads to 13 and dianellinone (2a). The synthesis confirms the 3.3′-dimerisation of the natural product.