Pragmatic approach and variations in the management of pregnant women with type 1 diabetes mellitus on insulin pump: a case series

Author:

Nargunan Varuna1ORCID,Enakpene Christopher A.2ORCID,Bennion Glen3,Merugumala Praveen D.4,Brown Elisa3,Schlabritz-Loutsevitch Natalia3

Affiliation:

1. Procare Endocrinology, Medical Center Hospital System , 315 North Golder , Odessa, TX 79761, USA , Tel.: +432-640-3052

2. Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , Texas Tech University Health Sciences Center , Permian Basin, TX , USA

3. Department of Obstetrics and Gynecology , Texas Tech University Health Sciences Center , Odessa, TX , USA

4. Texas Tech University Health Sciences Center, School of Medicine , Odessa, TX , USA

Abstract

Abstract Background According to a 2017 Centers for Disease Control and Prevention (CDC) report, there were 23.1 million Americans living with diagnosed diabetes. Diabetes-related complications in pregnancy are spontaneous abortion, preterm delivery, preeclampsia, fetal malformations, altered fetal growth, polyhydramnios, and unexplained fetal demise. Continuous insulin delivery through insulin pump is used for effective management of type 1 diabetes (T1DM). Case presentation We present case reports of four patients who were on insulin pump for at least 1 year prior to pregnancy and continued throughout their pregnancy. Although these case reports demonstrated overall good pregnancy outcomes, it did not show how well their blood glucose was controlled during pregnancy. Conclusion Standard of care in diabetic management during pregnancy using insulin pump in the presented case reports supports the American Association of Clinical Endocrinologists recommendation that insulin pump should be used for women with preexisting T1DM during pregnancy.

Publisher

Walter de Gruyter GmbH

Subject

Obstetrics and Gynaecology,Embryology,Pediatrics, Perinatology, and Child Health

Reference18 articles.

1. Center for Disease Control. National diabetes Factsheet: general information and national estimates on diabetes in the United States, 2017. Atlanta, GA: Centers for Disease Control and Prevention, Department of Health and Human Services, 2017; 2018.

2. Vargas R, Repke JT, Ural SH. Type 1 diabetes mellitus and pregnancy. Rev Obstet Gynecol. 2010;3:92–100.

3. Uzun Cilingir IG. Pregnancy outcomes in women with strictly controlled type 1 diabetes mellitus. Indian J Endocrinol Metab. 2018;22:798–800.

4. Wahabi HA, Esmaeil SA, Fayed A, Al-Shaikh G, Alzeidan RA. Pre-existing diabetes mellitus and adverse pregnancy outcomes. BMC Res Notes. 2012;5:496.

5. Holmes VA, Young IS, Patterson CC, Pearson DW, Walker JD, Maresh MJ, et al. Optimal glycemic control, pre-eclampsia, and gestational hypertension in women with type 1 diabetes in the diabetes and pre-eclampsia intervention trial. Diabetes Care. 2011;34:1683–8.

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