Author:
Lal Ann K.,Hibbard Judith U.
Abstract
AbstractAntithrombin III deficiency is an inherited thrombophilia that places pregnant patients at an increased risk of venous thromboembolism and adverse outcomes in pregnancy. Antithrombin III-deficient patients undergoing obstetric procedures may benefit from antithrombin III infusions during labor and delivery.The patient is a 32-year-old G2P1000 with known antithrombin III deficiency and factor V Leiden heterozygosity with a prior intrauterine fetal demise. The patient was managed with therapeutic enoxaparin until 37 weeks’ gestation when she was changed to IV heparin and plasma-derived antithrombin III. She underwent successful induction of labor, epidural anesthesia, and had an uncomplicated vaginal delivery.Plasma-derived antithrombin III can be used intrapartum for successful delivery in a patient with antithrombin III deficiency.
Subject
Obstetrics and Gynaecology,Embryology,Pediatrics, Perinatology, and Child Health
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