Influence of genetic polymorphisms of CYP3A5 and ABCB1 on sirolimus pharmacokinetics, patient and graft survival and other clinical outcomes in renal transplant-Reference-Cited by-同舟云学术

Influence of genetic polymorphisms of CYP3A5 and ABCB1 on sirolimus pharmacokinetics, patient and graft survival and other clinical outcomes in renal transplant

Published:2017-01-01 Issue:1 Volume:32 Page:
ISSN:2363-8915
Container-title:Drug Metabolism and Personalized Therapy
language:
Short-container-title:

Author:

Rodríguez-Jiménez Consuelo,García-Saiz Mar,Pérez-Tamajón Lourdes,Salido Eduardo,Torres Armando

Abstract

AbstractBackground:In transplant patients receivingMethods:Forty-eight renal transplant recipients (suffered 48% diabetes mellitus, 91% hypertension, and 47% dyslipidemia) were genotyped forResults:1/Conclusions:and

Publisher

Walter de Gruyter GmbH

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

https://www.degruyter.com/document/doi/10.1515/dmpt-2016-0040/pdf

Reference80 articles.

1. Sirolimus and everolimus in kidney transplantation;Drug Discov Today,2015

2. Frequency distribution of C3435T mutation in exon 26 of the MDR1 gene in a Spanish population;Ther Drug Monit,2003

3. Kidney transplantation without calcineurin inhibitor drugs: a prospective, randomized trial of sirolimus versus cyclosporine;Transplantation,2002

4. Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation;Am J Transplant,2005

5. Sirolimus: the evidence for clinical pharmacokinetic monitoring;Clin Pharmacokinet,2005

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Associations Between CYP3A5 (c.6986A>G) Gene Polymorphism and Kidney Impairment in Hypertensive Adults Without Cystatin C Elevation;Cardiovascular Toxicology;2024-08-02

2. Retrospective pharmacogenetic study in a cohort of pediatric tuberous sclerosis complex patients using everolimus;Pharmacogenomics;2023-10

3. Central nervous system manifestations of LRBA deficiency: case report of two siblings and literature review;BMC Pediatrics;2023-07-13

4. Influence of genetic variants on the pharmacokinetics and pharmacodynamics of sirolimus: a systematic review;Pharmacogenomics;2023-07

5. Precision sirolimus dosing in children: The potential for model-informed dosing and novel drug monitoring;Frontiers in Pharmacology;2023-03-20