Chemical Composition and in vitro Antimicrobial Activity of the Essential Oils of Two Helichrysum Species from Tanzania

Author:

Bougatsos Christos1,Ngassapa Olipa2,Runyoro Deborah K. B.2,Chinou Ioanna B.1

Affiliation:

1. Laboratory of Pharmacognosy - Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, GR-15771 Athens, Greece

2. Department of Pharmacognosy, School of Pharmacy, Muhimbili University College of Health Sciences, P. O. Box 65013, Dar Es Salaam, Tanzania

Abstract

The chemical composition of the essential oils obtained from the aerial parts of Helichrysum cymosum and H. fulgidum, from Tanzania, were analyzed by GC and GC/MS. A total of sixty-five compounds, representing 92.4% and 88.2% of the two oils, respectively, were identified. trans-Caryophyllene, caryophyllene oxide, β-pinene, p-cymene, spathulenol and β- bourbonene were found to be the main components. Furthermore, the oils were tested against six gram (±) bacteria and three pathogenic fungi. It was found that the oil of H. fulgidum exhibited significant antimicrobial activity, while the oil of H. cymosum was not active at all.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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