The correlation between self-related adherence, asthma-related quality of life and control of asthma in adult patients-Reference-Cited by-同舟云学术

The correlation between self-related adherence, asthma-related quality of life and control of asthma in adult patients

Published:2021-06-25 Issue:4 Volume:32 Page:453-458
ISSN:2191-0286
Container-title:Journal of Basic and Clinical Physiology and Pharmacology
language:en
Short-container-title:

Author:

Zairina Elida¹²³^ORCID,Nugraheni Gesnita¹²^ORCID,Achmad Gusti Noorrizka Veronika¹²^ORCID,Sulistyarini Arie¹²,Nita Yunita¹²,Bakhtiar Arief⁴⁵,Amin Muhammad⁴⁵

Affiliation:

1. Department of Pharmacy Practice , Faculty of Pharmacy, Universitas Airlangga , Surabaya , Indonesia

2. Innovative Pharmacy Practice and Integrated Outcomes Research (INACORE) Group , Universitas Airlangga , Surabaya , Indonesia

3. Center for Patient Safety Research , Universitas Airlangga , Surabaya , Indonesia

4. Department of Pulmonology and Respiratory Medicine , Faculty of Medicine, Universitas Airlangga , Surabaya , Indonesia

5. Department of Pulmonology , Universitas Airlangga Hospital , Surabaya , Indonesia

Abstract

Abstract Objectives Medication non-adherence mostly occurs in patients with a wide range of disease severity, including asthma. The aim of the study was to assess the self reported adherence to asthma therapy and investigate the relationship between adherence, asthma control and asthma-related quality of life. Methods The study was a cross-sectional study in which participants were recruited from an outpatient department, in one hospital in Surabaya. Patients (aged≥18 years) with asthma who had used any regular asthma medications were included. Standardised questionnaires, including Juniper’s Asthma Control Questionnaire (ACQ), Adherence to Refills and Medications Scales (ARMS) and Juniper’s Asthma Quality of Life Questionnaire (AQLQ) were used. Results A total of 82 adults with asthma were recruited in the study. Male participants’ mean age was 49.13 ± 14.10 years (n = 23). Approximately 59 participants (72.0%) were females, 30 participants (36.5%) were using Budesonide inhaler, and 73 participants (89.0%) never smoked. The mean of ACQ, AQLQ, and ARMS scores were 1.62 ± 1.19, 4.96 ± 1.24, and 16.98 ± 4.12, respectively. Of 82 patients studied 53 (64.6 %) had “uncontrolled asthma” and more than 85% participants both showed “non adherence” to asthma therapy and nearly 46% of them indicated that their quality of life was affected by asthma. There was a significant association between ACQ and AQLQ (p<0.05), whereas no statistically significant association was found between ACQ and ARMS. Conclusions The majority of patients reported non-adherence to asthma medications. Poor controlled asthma has been associated with lower asthma-related quality of life.

Publisher

Walter de Gruyter GmbH

Subject

Drug Discovery,Pharmacology,General Medicine,Physiology

Link

https://www.degruyter.com/document/doi/10.1515/jbcpp-2020-0434/pdf

Reference25 articles.

1. National Asthma Council of Australia. Diagnosis and classification in adults in asthma management handbook. Melbourne, Australia: National Asthma Council, Ltd; 2006.

2. Masoli, M, Fabian, D, Holt, S, Beasley, R. The global burden of asthma: executive summary of the GINA dissemination committee report. Allergy 2004;59.

3. Global Initiative for Asthma (GINA) Report. Global strategy for asthma management and prevention, from the global strategy for asthma management and prevention, global initiative for asthma (GINA); 2015. Available from: http://www.ginaasthma.org/.

4. Bousquet, J, Bousquet, PJ, Godard, P, Daures, J-P. The public health implications of asthma. Bull World Health Organ 2005;83:548–54.

5. Oh, EG. The relationship between disease control, symptom distress, functioning, and quality of life in adults with asthma. J Asthma: Off J Assoc Care Asthma 2008;45:882–6.