Author:
Zhao Jingjie,Guo Xu,Du Yi,Han Yu,Wang Yongzhi,Li Li,Qian Jialin,Li Mingzhen,Wu Huijuan,Golden Teresa,Wu Ning
Abstract
AbstractBackground:Major depressive disorder (MDD) frequently co-occurs with other psychiatric problems. Our previous study showed thatMethods:All participant patients were diagnosed by Diagnostic and Statistical Manual of Mental Disorders – 4th edition (DSM-IV). Hamilton rating scale for depression (HAM-D) and anxiety (HAM-A) were applied to group patients into different categories.Results:expression levels of all MDD subgroups showed significant reduction compared to the control group (p<0.01). Further, the trend ofConclusions:expression level reduction is related to MDD anxiety score, which may be an explanation for the clinical manifestations and the underlining physiological mechanisms.
Subject
Drug Discovery,Pharmacology,General Medicine,Physiology
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