Interplay between male gonadal function and overall male health-Reference-Cited by-同舟云学术

Interplay between male gonadal function and overall male health

Published:2024-05-01 Issue:3 Volume:35 Page:105-110
ISSN:2191-0286
Container-title:Journal of Basic and Clinical Physiology and Pharmacology
language:en
Short-container-title:

Author:

Asero Vincenzo¹,Scornajenghi Carlo Maria¹,Iaconis Salvatore²,Sicignano Enrico²^ORCID,Falcone Alfonso³,Dinacci Fabrizio⁴,Pagano Giovanni⁵,Carino Dalila⁶,Corvino Roberta⁶,Tresh Anas⁷

Affiliation:

1. Department of Maternal Infant and Urologic Sciences , 9311 University of Rome La Sapienza , Rome , Lazio , Italy

2. Department of Neuroscience and Reproductive and Odontostomatological Sciences , 165474 Federico II University Hospital , Napoli , Italy

3. Department of Neurosciences, Science of Reproduction and Odontostomatology , 9307 University of Naples Federico II , Napoli , Campania , Italy

4. Department of Neuroscience and Reproductive and Odontostomatological Sciences , 165474 Federico II University Hospital , Napoli , Campania , Italy

5. Department of Neurosciences, Science of Reproduction and Odontostomatology , 9307 University of Naples Federico II , Napoli , Italy

6. Department of Maternal Infant and Urologic Sciences , 9311 University of Rome La Sapienza , Rome , Italy

7. Department of Urology , 10624 Stanford University School of Medicine , Stanford , CA , USA

Abstract

Abstract The process-of-male reproduction is intricate, and various medical conditions-have the potential to disrupt spermatogenesis. Moreover, infertility in males can serve as an indicator of-potential future health issue. Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, psychological stress, environmental factors, and others. Consequently, infertility assessment-presents an opportunity for comprehensive health counseling, extending-beyond discussions about reproductive goals. Furthermore, male infertility has been suggested as a harbinger of future health problems, as poor semen quality and a diagnosis of-male infertility are associated with an increased risk of hypogonadism, cardiometabolic disorders, cancer, and even mortality. This review explores the existing-literature on the relationship between systemic illnesses and male fertility, impacting both clinical-outcomes and semen parameters. The majority of the literature analyzed, which compared gonadal function with genetic, chronic, infectious or tumoral diseases, confirm the association between overall male health and infertility.

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/jbcpp-2024-0054/pdf

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