Targeting Rho GTPase regulators in cancer: are we hitting the mark?-Reference-Cited by-同舟云学术

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Targeting Rho GTPase regulators in cancer: are we hitting the mark?

Published:2024-07-17 Issue: Volume: Page:
ISSN:0792-6855
Container-title:Journal of Basic and Clinical Physiology and Pharmacology
language:en
Short-container-title:

Author:

Alwan Shukrya H.¹,Baban Rayah S.²,Abid Hussein A.³^ORCID

Affiliation:

1. Department of Community Health , Technical Institute of Karbala, Al-Furat Al-Awsat Technical University , Karbala , Iraq

2. Department of Chemistry and Biochemistry , College of Medicine, Al-Nahrain University , Kadhimiya , Baghdad , Iraq

3. Department of Laboratory Diagnostics , Faculty of Health Sciences, University of Pécs , Pécs , Hungary

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/jbcpp-2023-0261/pdf

Reference8 articles.

1. Crosas-Molist, E, Samain, R, Kohlhammer, L, Orgaz, JL, George, SL, Maiques, O, et al.. Rho GTPase signaling in cancer progression and dissemination. Physiol Rev 2022;102:455–510. https://doi.org/10.1152/physrev.00045.2020.

2. Hodge, RG, Ridley, AJ. Regulating Rho GTPases and their regulators. Nat Rev Mol Cell Biol 2016;17:496–510. https://doi.org/10.1038/nrm.2016.67.

3. Barrio-Real, L, Kazanietz, MG. Rho GEFs and cancer: linking gene expression and metastatic dissemination. Sci Signal 2012;5. https://doi.org/10.1126/scisignal.2003543.

4. Dütting, S, Heidenreich, J, Cherpokova, D, Amin, E, Zhang, S-C, Ahmadian, MR, et al.. Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets. J Thromb Haemostasis 2015;13:827–38. https://doi.org/10.1111/jth.12861.

5. Orgaz, JL, Crosas-Molist, E, Sadok, A, Perdrix-Rosell, A, Maiques, O, Rodriguez-Hernandez, I, et al.. Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance. Cancer Cell 2020;37:85–103.e9. https://doi.org/10.1016/j.ccell.2019.12.003.

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