Counting and mapping of subwavelength nanoparticles from a single shot scattering pattern
Author:
Chan Eng Aik1ORCID, Rendón-Barraza Carolina1, Wang Benquan1, Pu Tanchao2, Ou Jun-Yu2, Wei Hongxin3, Adamo Giorgio1ORCID, An Bo3, Zheludev Nikolay I.12
Affiliation:
1. Centre for Disruptive Photonic Technologies, The Photonics Institute, School of Physical and Mathematical Sciences , Nanyang Technological University , 637371 Singapore , Singapore 2. Centre for Photonic Metamaterials and Optoelectronics Research Centre , University of Southampton , Southampton SO17 1BJ , UK 3. School of Computer Science and Engineering , Nanyang Technological University , 639798 Singapore , Singapore
Abstract
Abstract
Particle counting is of critical importance for nanotechnology, environmental monitoring, pharmaceutical, food and semiconductor industries. Here we introduce a super-resolution single-shot optical method for counting and mapping positions of subwavelength particles on a surface. The method is based on the deep learning analysis of the intensity profile of the coherent light scattered on the group of particles. In a proof of principle experiment, we demonstrated particle counting accuracies of more than 90%. We also demonstrate that the particle locations can be mapped on a 4 × 4 grid with a nearly perfect accuracy (16-pixel binary imaging of the particle ensemble). Both the retrieval of number of particles and their mapping is achieved with super-resolution: accuracies are similar for sets with closely located optically unresolvable particles and sets with sparsely located particles. As the method does not require fluorescent labelling of the particles, is resilient to small variations of particle sizes, can be adopted to counting various types of nanoparticulates and high rates, it can find applications in numerous particles counting tasks in nanotechnology, life sciences and beyond.
Funder
Singapore Ministry of Education Engineering and Physical Sciences Research Council National Research Foundation Singapore
Publisher
Walter de Gruyter GmbH
Subject
Electrical and Electronic Engineering,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials,Biotechnology
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