Interactions of Concanavalin A with the Membrane of Influenza Virus Infected Cells and with Envelope Components of the Virus Particle

Abstract

Treatment of host cells with Concanavalin A prevents the assembly or release of fowl plague virus from chick fibroblasts and inhibits fusion of BHK cells by the paramyxovirus SV5. Metabolic events of the host cells are not greatly impaired during the early phase of infection. There is evidence that the carbohydrate moiety of the Con A receptor of fowl plague virus is associated with the viral neuraminidase.