Radiobromine and radioiodine for medical applications-Reference-Cited by-同舟云学术

Radiobromine and radioiodine for medical applications

Published:2019-08-17 Issue:9-11 Volume:107 Page:1033-1063
ISSN:2193-3405
Container-title:Radiochimica Acta
language:en
Short-container-title:

Author:

Wilbur D. Scott¹,Adam Michael J.²

Affiliation:

1. Department of Radiation Oncology, Box 355016 , University of Washington , 616 N.E. Northlake Place , Seattle, WA 98105 , USA

2. TRIUMF/UBC , Vancouver, British Columbia , Canada

Abstract

Abstract The halogens bromine and iodine have similar chemical properties and undergo similar reactions due to their closeness in Group 17 of the periodic chart. There are a number of bromine and iodine radionuclides that have properties useful for diagnosis and therapy of human diseases. The emission properties of radiobromine and radioiodine nuclides with half-lives longer than 1 h are summarized along with properties that make radionuclides useful in PET/SPECT imaging and β/Auger therapy, such that the reader can assess which of the radionuclides might be useful for medical applications. An overview of chemical approaches that have been used to radiolabel molecules with radiobromine and radioiodine nuclides is provided with examples. Further, references to a large variety of different organ/cancer-targeting agents utilizing the radiolabeling approaches described are provided.

Funder

Nuclear Physics

Publisher

Walter de Gruyter GmbH

Subject

Physical and Theoretical Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/ract-2019-0004/pdf

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