Author:
Sanad M. H.,Ibrahim Alhussein A.
Abstract
AbstractIn the present work, [99mTc]N-histamine has been labeled using [99mTc≡N]2+core. Factors such as, amount of substrate, pH, reaction temperature,in vitrostability and reaction time, have been systematically studied to optimize high radiochemical purity (>99±0.3). Biodistribution studies indicate the suitability of [99mTc]N-histamine as a novel tracer to image brain. The complex of [99mTc]N-histamine may be considered a highly selective radiotracer for brain imaging.
Subject
Physical and Theoretical Chemistry
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