Affiliation:
1. 1Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, SK-832 32 Bratislava, Slovakia Republic
2. 2Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, Bratislava, Slovakia Republic
3. 3Toxicological and Antidoping Center, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, Bratislava, Slovakia Republic
Abstract
AbstractThis review summarized and analyzed the structural parameters of 174 monomeric organoplatinum complexes with an inner coordination sphere of trans-PtP2C2. These complexes crystallized in four crystal systems: hexagonal (x2), orthorhombic (x13), triclinic (x76), and monoclinic (x84). These complexes, on the basis of the coordination mode of the respective donor ligands, can be divided into the seven sub-groups: Pt(PL)2(CL)2, Pt(PL)2(η2-C2L), Pt(η2-P2L)(CL)2, Pt(PL)(η2-P,CL)(CL), Pt(η2-P,CL)2, Pt(η3-P,C,PL)(CL), and Pt(η3-C,P,CL)(PL). The chelating ligands create 4-, 5-, 6-, 16-, 17-, 18-, and 19-membered rings. The total mean values of Pt-L bond distances are 2.055 Å (C) and 2.300 Å (P). There are examples that exist in two isomeric forms and are examples of distortion isomerism. The structural parameters of trans-PtP2C2 are discussed with those of cis-PtP2C2 derivatives.