Author:
Bártová Markyta,Ryba Miloš,Jedličková Zdena,Novotný Ladislav,Hřebabecký Hubert,Beránek Jiří
Abstract
The inhibition of growth of Escherichia coli B by series of 6-azaanalogs of pyrimidine nucleosides, their precursors, and analogs of cancerostatic agents 5-fluorouracil and arabinosylcytosine is reported. A very high antibacterial activity is observed with most of the 5-fluorouracil nucleosides where a cleavage (30%) to 5-fluorouracil is observed at the most active compounds (5-fluorouridine, 5-fluoro-2'-deoxyuridine). Arabinosylcytosine and its derivatives express very low activity.
Publisher
Institute of Organic Chemistry & Biochemistry
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献