Polar alkaloids from Papaver orientale L.

Abstract

Corytuberine (I) and quaternary alkaloids N-methylhebainium hydroxide (II), N-methylisothebainium hydroxide (III), and magnoflorine (IV) as iodides have been isolated for the first time from the fraction of strongly polar alkaloids obtained from aerial parts and roots of Papaver orientale L. The weakly polar fraction contains oripavine, thebaine, isothebaine, and alpinigenine as dominant components. Small amounts of bracteoline, isoboldine, scoulerine, papaverrubines G, A, B, D, and C, and traces of palmatine and coptisine have also been detected.