Reactions of isothiocyanates and isocyanates with some silylated nitrogen-containing nucleophiles

Abstract

Aryl isothiocyanates and arylisocyanates react with N,O-bis(trimethylsilyl)acetamide to give N-methyl-N’-arylthioureas and ureas. Also nucleophilic additions of other aprotic nucleophiles (e.g. N-trimethylsilylimidazole, N-trimethylsilylpiperidine and N-trimethylsilylmorpholine) to the N=C=X (X = O, S) group were investigated.