Three New Alkaloids, Convolutamines F and G, and Convolutamydine E, from the Floridian Marine Bryozoan Amathia convoluta

Author:

Kamano Yoshiaki,Kotake Ayano,Hashima Hirofumi,Hayakawa Ichiro,Hiraide Hatsue,Zhang Hui-ping,Kizu Haruhisa,Komiyama Kanki,Hayashi Masahiko,Pettit George R.

Abstract

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxyoxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

Publisher

Institute of Organic Chemistry & Biochemistry

Subject

General Chemistry

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