Steroid and bile acids amide conjugates with D-glucosamine
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Published:2011
Issue:1
Volume:76
Page:65-74
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ISSN:1212-6950
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Container-title:Collection of Czechoslovak Chemical Communications
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language:en
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Short-container-title:Collect. Czech. Chem. Commun.
Author:
Nováková Zdena,Tomanová Jana,Štěrbová Lucie,Drašar Pavel
Abstract
New type of amide conjugates of steroid and bile acids with D-glucosamine 1 and 2 were prepared. Title compounds are prepared via acid chloride or using N-[({[(1E)-1-cyano-2-ethoxy-2-oxoethylidene]amino}oxy)(dimethylamino)methylidene]-N-methylmethanaminium tetrafluoroborate as condensation agent. They were examined for gelation properties with negative results. Per-O-acetylated D-glucosamine hydrochloride was prepared in one step procedure from D-glucosamine hydrochloride by acetylation in a mixture of acetyl chloride and acetic acid.
Publisher
Institute of Organic Chemistry & Biochemistry
Subject
General Chemistry