Synthesis and Biological Activity of 7a-Homo- and 7a,7b-Dihomo-5α-cholestane Analogues of Brassinolide-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of 7a-Homo- and 7a,7b-Dihomo-5α-cholestane Analogues of Brassinolide

Published:2003 Issue:11 Volume:68 Page:2171-2189
ISSN:0010-0765
Container-title:Collection of Czechoslovak Chemical Communications
language:en
Short-container-title:Collect. Czech. Chem. Commun.

Author:

Šíša Miroslav,Buděšínský Miloš,Kohout Ladislav

Abstract

New analogues of castasterone, (20R)-2α,3α-dihydroxy-7a-homo-5α-cholestan-7-one (12) and (20R)-3α,4α-dihydroxy-7a-homo-5α-cholestan-7-one (14), and brassinolide, (20R)-2α,3α-dihydroxy-7a,7b-dihomo-7a-oxa-5α-cholestan-7-one (15), (20R)-3α,4α-dihydroxy-7a,7b-dihomo-7a-oxa-5α-cholestan-7-one (16) and (20R)-7-oxa-7a-homo-5α-cholestan-2α,3α-diol (24), were synthesized and their biological and spectral properties studied.

Publisher

Institute of Organic Chemistry & Biochemistry

Subject

General Chemistry

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