Author:
Špirková Katarína,Stankovský Štefan,Dandárová Miloslava
Abstract
The paper describes the cyclization reactions of substituted 1-(4'-quinazolyl)-4-phenylthiosemicarbazides (Ia - Ie). The thermal intramolecular cyclization gives 2H-1,2,4-triazolo[4,3-c]quinazoline-3-thiones (IIa - IId). Heating of I with HgO gives 3-anilino-1,2,4-triazolo[4,3-c]quinazolines (IIIa - IIIe). The IR and 1H NMR spectra of the compounds synthesized are presented.
Publisher
Institute of Organic Chemistry & Biochemistry
Cited by
8 articles.
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1. Triazoloquinazoline: Synthetic Strategies and Medicinal Importance;Recent Advances on Quinazoline [Working Title];2023-11-13
2. 2-Heteroaryl-[1,2,4]triazolo[1,5-c]quinazoline-5(6 H)-thiones and Their S-Substituted Derivatives: Synthesis, Spectroscopic Data, and Biological Activity;ChemPlusChem;2015-03-04
3. ChemInform Abstract: Synthesis of Some 1,2,4-Triazolo(4,3-c)quinazolines Based on 4- Quinazolylthiosemicarbazides.;ChemInform;2010-08-19
4. An Efficient Three-Component Synthesis of 3-(1-Hydroxyalkyl)[1,2,4]-triazolo[4,3-c]quinazolines;Synlett;2010-03-02
5. References;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02