Alkaloids from Papaver pinnatifidum MORIS

Abstract

Oripavine (Ia) was isolated from Papaver pinnatifidum MORIS (tetraploid, 2n = 28) of the section Rhoeadium SPACH as the major alkaloid. In a low yield, protopine and (+)-isocorydine were obtained together with a novel levorotatory alkaloid PP 1 of the composition C17H19NO3 and m.p. 179 °C, probably of a normorphinane type. Small amounts of thebaine, allocryptopine, scoulerine, isoboldine, and papaverrubines A, C and D, berberine, and corytuberine were also detected by thin layer chromatography.