Alternative syntheses of 2α,3α,17β-trihydroxy-7-oxa-B-homo-5α-androstan-6-one and some androstane brassinolide analogs

Abstract

The title compound XVI was synthesized from III, IV or V. Related compounds X, XIII, XVI, XVIII, XXIII, XXIV, XXVII, XXVIII, XXXV, XXXVI, XLI, and XLIII were also prepared and tested by bean second internode bioassay. They showed only low activity (by about 2-3 orders or even lower than 24-epibrassinolide).