The effect of some structural modifications of the oxytocin molecule on the duration of the galactogogic response-Reference-Cited by-同舟云学术

The effect of some structural modifications of the oxytocin molecule on the duration of the galactogogic response

Published:1981 Issue:10 Volume:46 Page:2441-2445
ISSN:0010-0765
Container-title:Collection of Czechoslovak Chemical Communications
language:en
Short-container-title:Collect. Czech. Chem. Commun.

Author:

Barth Tomislav,Slaninová Jiřina,Servítová Linda,Lebl Michal,Kotsira-Engonopoulos Christine,Tzougraki Chrysa,Photaki Iphigenia,Krojidlo Milan,Jošt Karel

Abstract

The duration of the galactogogic response to analogues of oxytocin, modified mainly in the aminoterminal part of the molecule, was determined in experiments with lactating rats. The influence of the individual structural modifications was investigated by determining the dependence of both the intensity of the effect and the total effect of the compound on the log dose.

Publisher

Institute of Organic Chemistry & Biochemistry

Subject

General Chemistry

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