Author:
Hocek Michal,Holý Antonín
Abstract
A facile method of preparation of 6-cyanopurine bases from commercially available 6-chloropurines is reported. The 6-chloropurines were selectively protected by THP-functions and the protected derivatives reacted smoothly with tetraethylammonium cyanide and DABCO to give 6-cyanopurine derivatives that were easily deprotected to afford the title compounds.
Publisher
Institute of Organic Chemistry & Biochemistry
Cited by
32 articles.
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