Synthesis of Alkyl 1,2-Dicyanopyrrolidino[1,2-f]phenanthridine-3-carboxylates

Abstract

Alkyl 1,2-dicyanopyrrolidino[1,2-f]phenanthridine-3-carboxyla tes II were prepared from 5-(alkoxycarbonylmethyl)phenanthridinium bromides I and fumaronitrile in the presence of triethylamine. The products II underwent spontaneous dehydrogenation to give pyrrolino[1,2-f]phenanthridines III. The structures of the products were determined by spectral methods (IR, NMR, MS).