Spectrofluorimetric Study on Inclusion Complexation of 2-Amino-6-fluorobenzothiazole with β-Cyclodextrin

Abstract

The interaction between 2-amino-6-fluorobenzothiazole (AFBT) and β-cyclodextrin (β-CDx) has been investigated in aqueous solution and in the solid state. The stoichiometry and binding constant of the complex between AFBT and β-CDx in solution were determined by steady-state and time-resolved fluorescence spectroscopy. The FT-IR spectral data and SEM images of the solid complex confirmed the formation of inclusion complex. The proton transfer behaviour of AFBT has been investigated in aqueous and β-CDx solutions.