Stereochemistry of NaBH4 Reduction of a 19-Carbonyl Group of 3-Deoxy Androgens. Synthesis of [19S-3H]- and [19R-3H]-Labeled Aromatase Inhibitors Having a 19-Hydroxy Group-Reference-Cited by-同舟云学术

Stereochemistry of NaBH4 Reduction of a 19-Carbonyl Group of 3-Deoxy Androgens. Synthesis of [19S-3H]- and [19R-3H]-Labeled Aromatase Inhibitors Having a 19-Hydroxy Group

Published:2004 Issue:6 Volume:52 Page:722-726
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Numazawa Mitsuteru¹,Sohtome Norishige¹,Nagaoka Masao¹

Affiliation:

1. Tohoku Pharmaceutical University

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/52/6/52_6_722/_pdf

Reference23 articles.

1. The Involvement of Human Placental Microsomal Cytochrome P-450 in Aromatization

2. Purification and characterization of human placental aromatase cytochrome P-450.

3. Purification of human placental aromatase cytochrome P-450 with monoclonal antibody and its characterization

4. Utilization of Oxygen and Reduced Nicotinamide Adenine Dinucleotide Phosphate by Human Placental Microsomes during Aromatization of Androstenedione

5. Conversion of 19-hydroxy-Δ4-androstene-3,17-dione to estrone by endocrine tissue

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4. Gas chromatography–mass spectrometric analysis of oxidative reactions of [19,19-2H2]19-hydroxy-3-deoxy androgens by placental aromataseAbsence of a deuterium-isotope effect;Steroids;2005-11

5. Aromatase Reaction of 3-Deoxyandrogens: Steric Mode of the C-19 Oxygenation and Cleavage of the C10−C19 Bond by Human Placental Aromatase;Biochemistry;2005-07-22