The Antiarrhythmic Action of the Na+/Ca2+ Exchanger Inhibitor SEA0400 on Drug-Induced Long QT Syndrome Depends on the Severity of Proarrhythmic Conditions in Anesthetized Atrioventricular Block Rabbits-Reference-Cited by-同舟云学术

The Antiarrhythmic Action of the Na+/Ca2+ Exchanger Inhibitor SEA0400 on Drug-Induced Long QT Syndrome Depends on the Severity of Proarrhythmic Conditions in Anesthetized Atrioventricular Block Rabbits

Published:2023-08-01 Issue:8 Volume:46 Page:1120-1127
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biological & Pharmaceutical Bulletin

Author:

Kawakami Satoshi¹,Takada Kazuhiro¹,Aimoto Megumi¹,Nagasawa Yoshinobu¹,Kusakabe Taichi²,Kato Keisuke²,Takahara Akira¹

Affiliation:

1. Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Toho University

2. Department of Organic Chemistry, Faculty of Pharmaceutical Sciences, Toho University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/46/8/46_b23-00202/_pdf

Reference25 articles.

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2. 2) Yan GX, Wu Y, Liu T, Wang J, Marinchak RA, Kowey PR. Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome: direct evidence from intracellular recordings in the intact left ventricular wall. Circulation, 103, 2851–2856 (2001).

3. 3) Roden DM. Cellular basis of drug-induced torsades de pointes. Br. J. Pharmacol., 154, 1502–1507 (2008).

4. 4) Thomas SHL, Behr ER. Pharmacological treatment of acquired QT prolongation and torsades de pointes. Br. J. Clin. Pharmacol., 81, 420–427 (2016).

5. 5) Liao WB, Bullard MJ, Kuo CT, Hsiao CT, Chu PH, Chiang CW. Anticholinergic overdose induced torsade de pointes successfully treated with verapamil. Jpn. Heart J., 37, 925–931 (1996).

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