Trends in Implementation of Loading Dose of Voriconazole from 2010 to 2019 and Influencing Factors of Loading Dose Based on a Japanese Administrative Claim Database: A Retrospective Cohort Study

Author:

Inose Ryo1,Goto Ryota1,Shimoki Misato1,Ohmagari Norio2,Muraki Yuichi1

Affiliation:

1. Laboratory of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University

2. AMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference11 articles.

1. 1) Theuretzbacher U, Ihle F, Derendorf H. Pharmacokinetic/pharmacodynamic profile of voriconazole. Clin. Pharmacokinet., 45, 649–663 (2006).

2. 2) Purkins L, Wood N, Greenhalgh K, Eve MD, Oliver SD, Nichols D. The pharmacokinetics and safety of intravenous voriconazole—a novel wide-spectrum antifungal agent. Br. J. Clin. Pharmacol., 56 (Suppl. 1), 2–9 (2003).

3. 3) Hamada Y, Ueda T, Miyazaki Y, Nakajima K, Fukunaga K, Miyazaki T, Nakada-Motokawa N, Nagao M, Kawamura H, Shigemi A, Ebihara F, Kimura T, Ikegame K, Uchino M, Ikeuchi H, Takesue Y. Effects of antifungal stewardship using therapeutic drug monitoring in voriconazole therapy on the prevention and control of hepatotoxicity and visual symptoms: a multicentre study conducted in Japan. Mycoses, 63, 779–786 (2020).

4. 4) Dellit TH, Owens RC, McGowan JE Jr, Gerding DN, Weinstein RA, Burke JP, Huskins WC, Paterson DL, Fishman NO, Carpenter CF, Brennan PJ, Billeter M, Hooton TM. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin. Infect. Dis., 44, 159–177 (2007).

5. 5) Johnson MD, Lewis RE, Dodds Ashley ES, Ostrosky-Zeichner L, Zaoutis T, Thompson GR III, Andes DR, Walsh TJ, Pappas PG, Cornely OA, Perfect JR, Kontoyiannis DP. Core recommendations for antifungal stewardship: a statement of the mycoses study group education and research consortium. J. Infect. Dis., 222 (Suppl. 3), S175–S198 (2020).

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