Comparing the Efficacy of Fosnetupitant, an NK<sub>1</sub> Receptor Antagonist in CDDP-Based Regimens, with That of Fosaprepitant and Aprepitant: A Retrospective Observational Study

Author:

Inano Hiroshi1,Morimoto Yoshihito2,Kitagawa Kanata1,Shibuya Akito1,Nakagomi Kozue1,Ota Tomohiro1,Anzo Yuri1,Miyauchi Rika2,Shono Aiko3,Watanabe Kazuhiro2,Otori Katsuya14

Affiliation:

1. Department of Pharmacy, Kitasato University Hospital

2. Education and Research Center for Clinical Pharmacy, Showa Pharmaceutical University

3. Laboratory of Social Pharmacy and Regulatory Science, Showa Pharmaceutical University

4. Laboratory of Pharmacy Practice and Science I, Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University

Publisher

Pharmaceutical Society of Japan

Reference26 articles.

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2. 2) Osoba D, Zee B, Warr D, Latreille J, Kaizer L, Pater J. Effect of postchemotherapy nausea and vomiting on health-related quality of life. Support. Care Cancer, 5, 307–313 (1997).

3. 3) Schwartzberg LS, Modiano MR, Rapoport BL, Chasen MR, Gridelli C, Urban L, Poma A, Arora S, Navari RM, Schnadig ID. Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial. Lancet Oncol., 16, 1071–1078 (2015).

4. 4) Ithimakin S, Theeratrakul P, Laocharoenkiat A, Nimmannit A, Akewanlop C, Soparattanapaisarn N, Techawattanawanna S, Korphaisarn K, Danchaivijitr P. Randomized, double-blind, placebo-controlled study of aprepitant versus two dosages of olanzapine with ondansetron plus dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving high-emetogenic chemotherapy. Support. Care Cancer, 28, 5335–5342 (2020).

5. 5) Aogi K, Takeuchi H, Saeki T, et al. Optimizing antiemetic treatment for chemotherapy-induced nausea and vomiting in Japan: update summary of the 2015 Japan Society of Clinical Oncology clinical practice guidelines for antiemesis. Int. J. Clin. Oncol., 26, 1–17 (2021).

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