Ugi Adducts as Novel Anti-austerity Agents against PANC-1 Human Pancreatic Cancer Cell Line: A Rapid Synthetic Approach
Author:
Affiliation:
1. Faculty of Arts and Science, Kyushu University
2. Natural Drug Discovery Laboratory, Institute of Natural Medicine, University of Toyama
3. Graduate School of Science, Kyushu University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/46/10/46_b23-00224/_pdf
Reference33 articles.
1. 1) Vaziri-Gohar A, Cassel J, Mohammed FS, et al. Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors. Nat. Cancer, 3, 852–865 (2022).
2. 2) Tao J, Yang G, Zhou W, Qiu J, Chen G, Luo W, Zhao F, You L, Zheng L, Zhang T, Zhao Y. Targeting hypoxic tumor microenvironment in pancreatic cancer. J. Hematol. Oncol., 14, 14 (2021).
3. 3) Awale S, Lu J, Kalauni SK, Kurashima Y, Tezuka Y, Kadota S, Esumi H. Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation. Cancer Res., 66, 1751–1757 (2006).
4. 4) Tawila AM, Omar AM, Phan ND, Takahashi I, Maneenet J, Awale S. New callistrilone epimers from Callistemon citrinus and their antiausterity activity against the PANC-1 human pancreatic cancer cell line. Tetrahedron Lett., 100, 153881 (2022).
5. 5) Maneenet J, Tawila AM, Omar AM, Phan ND, Ojima C, Kuroda M, Sato M, Mizoguchi M, Takahashi I, Awale S. Chemical constituents of Callistemon subulatus and their anti-pancreatic cancer activity against human PANC-1 cell line. Plants (Basel), 11, 2466 (2022).
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2. Droserone and dioncoquinone B, and related naphthoquinones as potent antiausterity agents against human PANC-1 pancreatic cancer cells;Results in Chemistry;2024-01
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